Postdoctoral Fellow

At a glance

Position:Postdoctoral Fellow

Primary Location:Midland (MI, USA), Michigan, United States of America

Schedule:Full time

Date Posted:04/29/2024

Job Number:R2049874

Position Type:Temporary

At Dow, we believe in putting people first and we’re passionate about delivering integrity, respect and safety to our customers, our employees and the planet.

Our people are at the heart of our solutions. They reflect the communities we live in and the world where we do business. Their diversity is our strength. We’re a community of relentless problem solvers that offers the daily opportunity to contribute with your perspective, transform industries and shape the future. Our purpose is simple - to deliver a sustainable future for the world through science and collaboration. If you’re looking for a challenge and meaningful role, you’re in the right place.

Dowhas an exciting opportunity available within our Product Safety Research group that is part of our Toxicology and Environment Research & Consulting (TERC) Team. The location is inMidland, Michiganas this role is aligned to the laboratory where investigative research is conducted to ensure the sustainability of our chemistries. Specifically, we are looking for aPostdoctoral Candidatewith experience and training in toxicology, pharmacology, medicinal chemistry, or a related field. The postdoctoral candidate will work closely with TERC scientists in developing and applying state-of-the-art computational and/or in vitro toxicokinetic tools and conducting in vivo toxicokinetic studies to understand chemical Adsorption, Distribution, Metabolism and Excretion (ADME) and develop toxicokinetic models.

About you and this role:

This is a laboratory-based position, and the successful candidate is expected to be actively involved in research projects in toxicokinetics, including in vivo studies, in vitro toxicokinetics (e.g., metabolism, plasma protein binding), and the application of in vitro and in vivo datasets to in silico toxicokinetic models using GastroPlus®. The candidate will collaborate with TERC’s current Toxicokinetics expert as well as TERC’s Predictive Toxicology team (e.g., cheminformatics) to incorporate toxicokinetic data on metabolite predictions and/or internal dosimetry to provide context for other non-animal methods (NAMs) data. Activities include experimental design, study conduct, interpretation of results, and evaluation of assay performance. The candidate is expected to present research findings at internal and external workshops/meetings and publish in prestigious peer-reviewed journals. The postdoctoral position at Dow is for one-year and the contract is renewable up to two years.

Responsibilities:

• Provides science leadership and hands-on experience in conducting laboratory research studies to design, conduct and report in vivo toxicokinetic studies

• Designs and conducts in vitro studies to examine toxicokinetic parameters of interest (e.g., intrinsic clearance, species comparative metabolism, plasma protein binding)

• Performs toxicokinetic modeling using GastroPlus®

• Works with Dow Toxicokinetic experts and other Dow team members for robust application of NAM data streams to screen for chemical hazards

• Leads study team and leverages broader expertise to deliver high quality scientific results that are aligned with business and regulatory needs

• Develops and implements technical solutions through hands-on experimentation/problem solving for the investigative research

• Provides clear, concise communications both internally and externally including publications and presentations

• Understands and follows appropriate EH&S standards, policies, and procedures applicable to their job. Leads by example in the area of safety behaviors and promotes safe work habits

Required qualifications:

• A minimum of a Ph.D. is required. Fields in toxicology, pharmacology, medicinal chemistry or a related field required

• Experience conducting in vivo toxicokinetic studies, in vitro toxicokinetic parameter generation, and/or in silico toxicokinetic modeling

• Knowledge of polymer chemistry and/or analytical chemistry

Your skills, knowledge, and abilities include:

• Proven project management skills. Ability to define scope and deliverables, successfully lead a small to medium project to completion

• Strong safety mindset

• Strong inclusion, diversity and equity mindset

• Excellent verbal and written communication skills

• Strong ability to analyze and interpret study results

• Strong interpersonal skills. Proactively seeks to understand differences of opinions to resolve

• Work independently and within a multidisciplinary team setting

• Strong work ethic and attention to detail

• A passion for solving complex research problems and exploring the unknown

Note: This position does not offer relocation assistance​.

About Dow

Dow (NYSE: DOW) is one of the world’s leading materials science companies, serving customers in high-growth markets such as packaging, infrastructure, mobility and consumer applications. Our global breadth, asset integration and scale, focused innovation, leading business positions and commitment to sustainability enable us to achieve profitable growth and help deliver a sustainable future. We operate manufacturing sites in 31 countries and employ approximately 35,900 people. Dow delivered sales of approximately $45 billion in 2023. References to Dow or the Company mean Dow Inc. and its subsidiaries. ​​​​Learn more about us and our ambition to be the most innovative, customer-centric, inclusive and sustainable materials science company in the world by visitingwww.dow.com.

As part of our dedication to the diversity of our workforce, Dow is committed to equal opportunities in employment. We encourage every employee to bring their whole self to work each day to not only deliver more value, but also have a more fulfilling career. Further information regarding Dow's equal opportunities is available onwww.dow.com.

Dow is an Equal Employment Opportunity employer and is committed to providing opportunities without regard for race, color, religion, sex, including pregnancy, sexual orientation, or gender identity, national origin, age, disability and genetic information, including family medical history. We are also committed to providing reasonable accommodations for qualified individuals with disabilities and disabled veterans in our job application procedures. If you need assistance or an accommodation due to a disability, you may call us at 1-833-My Dow HR (833-693-6947) and select option 8.